Long-term exposure to air pollution linked to heightened autoimmune disease risk
By: Chloe Coules , Source: https://bit.ly/3qbVTUp
Long term exposure to air pollution is linked to a heightened risk of autoimmune disease, finds new research.
The study found environmental air pollution from vehicle exhausts and industrial output can trigger adaptive immunity – whereby the body reacts to a specific disease-causing entity – but sometimes this adaptive response misfired, prompting systemic inflammation, tissue damage, and ultimately autoimmune disease.
The research, published online in RMD Open, found the risk is especially high for developing certain autoimmune conditions including rheumatoid arthritis, connective tissue and inflammatory bowel diseases.
The incidence and prevalence of autoimmune diseases have steadily increased over the past decade, but the reasons for this are not yet clear.
The researchers mined the national Italian fracture risk database, tracking diagnoses of autoimmune diseases and linking participants to the nearest air quality monitoring system run by the Italian Institute of Environment Protection and Research.
They found exposure to PM2.5 was not associated with a heightened risk of an autoimmune disease...